Alzheimer's disease genetic risk variants beyond APOE ε4 predict mortality

INTRODUCTION: We hypothesized that, like apolipoprotein E (APOE), other late-onset Alzheimer's disease (LOAD) genetic susceptibility loci predict mortality. METHODS: We used a weighted genetic risk score (GRS) from 21 non-APOE LOAD risk variants to predict survival in the Adult Changes in Thoug...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Mez, Jesse, Marden, Jessica R., Mukherjee, Shubhabrata, Walter, Stefan, Gibbons, Laura E., Gross, Alden L., Zahodne, Laura B., Gilsanz, Paola, Brewster, Paul, Nho, Kwangsik, Crane, Paul K., Larson, Eric B., Glymour, M. Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604953/
https://ncbi.nlm.nih.gov/pubmed/28983503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.07.002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados