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TOMM40 intron 6 poly-T length, age-at-onset and neuropathology of AD in individuals with APOE ε3/ε3

BACKGROUND: This study investigates the association between TOMM40 poly-T length, age-at-onset, and neuropathology in Alzheimer’s disease (AD) individuals with the APOE ε3/ε3 allele. METHODS: Thirty-two PSEN1 mutation carriers with AD, 27 PSEN2 mutation carriers with AD, 59 participants with late-on...

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Detalhes bibliográficos
Main Authors: Li, Ge, Bekris, Lynn M., Leong, Lesley, Steinbart, Ellen J., Shofer, Jane B., Crane, Paul K., Larson, Eric B., Peskind, Elaine R., Bird, Thomas D., Yu, Chang-En
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606272/
https://ncbi.nlm.nih.gov/pubmed/23183136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2012.06.009
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