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The Effect of APOE-ε4 on Dementia is Mediated by Alzheimer Neuropathology

The degree to which the association of ε4 with dementia is mediated by AD lesions in comparison with vascular lesions is controversial. The present study was undertaken to determine the roles of Alzheimer (AD) and vascular pathology in mediating the effect of APOE-ε4 alleles on dementia. Clinicopath...

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Détails bibliographiques
Auteurs principaux: Mortimer, James A., Snowdon, David A., Markesbery, William R.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752689/
https://ncbi.nlm.nih.gov/pubmed/19484916
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