Age‐dependent effects of APOE ε4 in preclinical Alzheimer's disease

OBJECTIVE: The ε4 allele of apolipoprotein E (APOE) is the strongest known common genetic risk factor for Alzheimer's disease (AD) and alters age of onset in retrospective studies. Here, we longitudinally test the effects of APOE ε4 genotype and age during progression from normal cognition to A...

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Bibliografiset tiedot
Julkaisussa:Ann Clin Transl Neurol
Päätekijät: Bonham, Luke W., Geier, Ethan G., Fan, Chun C., Leong, Josiah K., Besser, Lilah, Kukull, Walter A., Kornak, John, Andreassen, Ole A., Schellenberg, Gerard D., Rosen, Howard J., Dillon, William P., Hess, Christopher P., Miller, Bruce L., Dale, Anders M., Desikan, Rahul S., Yokoyama, Jennifer S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018579/
https://ncbi.nlm.nih.gov/pubmed/27648456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.333
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