Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Recent advances in single-cell technologies have permitted the investigation of heterogeneous cell populations at previously unattainable resolution. Here we apply such approaches to resolve the molecular mechanisms driving disease in mouse hematopoietic stem cells (HSCs), using JAK2V617F mutant mye...

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Shepherd, Mairi S., Li, Juan, Wilson, Nicola K., Oedekoven, Caroline A., Li, Jiangbing, Belmonte, Miriam, Fink, Juergen, Prick, Janine C. M., Pask, Dean C., Hamilton, Tina L., Loeffler, Dirk, Rao, Anjana, Schröder, Timm, Göttgens, Berthold, Green, Anthony R., Kent, David G.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2018
Teme:
Hematopoiesis and Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107881/
https://ncbi.nlm.nih.gov/pubmed/29991556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-12-821066
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