Hematopoietic stem cells retain functional potential and molecular identity in hibernation cultures

Advances in the isolation and gene expression profiling of single hematopoietic stem cells (HSCs) have permitted in-depth resolution of their molecular program. However, long-term HSCs can only be isolated to near purity from adult mouse bone marrow, thereby precluding studies of their molecular pro...

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Pubblicato in:Stem Cell Reports
Autori principali: Oedekoven, Caroline A., Belmonte, Miriam, Bode, Daniel, Hamey, Fiona K., Shepherd, Mairi S., Che, James Lok Chi, Boyd, Grace, McDonald, Craig, Belluschi, Serena, Diamanti, Evangelia, Bastos, Hugo P., Bridge, Katherine S., Göttgens, Berthold, Laurenti, Elisa, Kent, David G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8190576/
https://ncbi.nlm.nih.gov/pubmed/33961793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2021.04.002
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