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Adeno-associated virus (AAV) site-specific recombination does not require a Rep-dependent origin of replication within the AAV terminal repeat

Adeno-associated virus (AAV) is the only known eukaryotic virus capable of targeted integration in human cells. An AAV Rep binding element (RBE) and terminal resolution site (trs) identical to the viral terminal repeats required for AAV DNA replication are located on chromosome (ch) 19. Both ch-19 R...

詳細記述

保存先:
書誌詳細
主要な著者: Young, Samuel M., Samulski, Richard Jude
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC61074/
https://ncbi.nlm.nih.gov/pubmed/11707592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241508998
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