The long tail of oncogenic drivers in prostate cancer

Comprehensive genomic characterization of prostate cancer has identified recurrent alterations in androgen signaling, DNA repair, and PI3K among others. However, larger and uniform genomic analysis may reveal additional recurrently mutated genes at lower frequencies. Here we aggregate and uniformly...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Armenia, Joshua, Wankowicz, Stephanie A.M., Liu, David, Gao, Jianjiong, Kundra, Ritika, Reznik, Ed, Chatila, Walid K., Chakravarty, Debyani, Han, G. Celine, Coleman, Ilsa, Montgomery, Bruce, Pritchard, Colin, Morrissey, Colm, Barbieri, Christopher E., Beltran, Himisha, Sboner, Andrea, Zafeiriou, Zafeiris, Miranda, Susana, Bielski, Craig M., Penson, Alexander V., Tolonen, Charlotte, Huang, Franklin W., Robinson, Dan, Wu, Yi Mi, Lonigro, Robert, Garraway, Levi A., Demichelis, Francesca, Kantoff, Philip W., Taplin, Mary-Ellen, Abida, Wassim, Taylor, Barry S., Scher, Howard I., Nelson, Peter S., de Bono, Johann S., Rubin, Mark A., Sawyers, Charles L., Chinnaiyan, Arul M., Schultz, Nikolaus, Van Allen, Eliezer M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107367/
https://ncbi.nlm.nih.gov/pubmed/29610475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0078-z
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