Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism

Mitochondrial dysfunction is a hallmark of metabolic diseases such as obesity, type 2 diabetes mellitus, neurodegenerative diseases, and cancers. Dysfunction occurs in part because of altered regulation of the mitochondrial pyruvate dehydrogenase complex (PDC), which acts as a central metabolic node...

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Detalhes bibliográficos
Publicado no:Diabetes Metab J
Main Authors: Park, Sungmi, Jeon, Jae-Han, Min, Byong-Keol, Ha, Chae-Myeong, Thoudam, Themis, Park, Bo-Yoon, Lee, In-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Diabetes Association 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107359/
https://ncbi.nlm.nih.gov/pubmed/30136450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2018.0101
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