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Pendant HDAC Inhibitor SAHA Derivatized Polymer as a Novel Prodrug Micellar Carrier for Anticancer Drugs

Suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor (HDACI) approved by FDA for the treatment of cutaneous T cell lymphoma, is a promising anticancer drug for various cancers with a unique mode of action. However, it demonstrates limited clinical benefits in solid tumors as a sin...

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Bibliografske podrobnosti
izdano v:J Drug Target
Main Authors: Xu, Jieni, Sun, Jingjing, Wang, Pengcheng, Ma, Xiaochao, Li, Song
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107352/
https://ncbi.nlm.nih.gov/pubmed/29251528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/1061186X.2017.1419355
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