A Prodrug Micellar Carrier Assembled from Polymers with Pendant Farnesyl Thiosalicylic Acid Moieties for Improved Delivery of Paclitaxel

In order to achieve enhanced and synergistic delivery of paclitaxel (PTX), a hydrophobic anticancer agent, two novel prodrug copolymers, POEG(15)-b-PFTS(6) and POEG(15)-b-PFTS(16) composed of hydrophilic poly(oligo(ethylene glycol) methacrylate) (POEG) and hydrophobic farnesylthiosalicylate (FTS, a...

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Publicado no:Acta Biomater
Main Authors: Sun, Jingjing, Chen, Yichao, Li, Ke, Huang, Yixian, Fu, Xiaofeng, Zhang, Xiaolan, Zhao, Wenchen, Wei, Yuan, Xu, Liang, Zhang, Peijun, Venkataramanan, Raman, Li, Song
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5012958/
https://ncbi.nlm.nih.gov/pubmed/27422196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2016.07.014
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