A PEG-Fmoc conjugate as a nanocarrier for paclitaxel

We report here that a simple, well-defined, and easy-to-scale up nanocarrier, PEG(5000)-lysyl-(α-Fmoc-ε-t-Boc-lysine)(2) conjugate (PEG-Fmoc), provides high loading capacity, excellent formulation stability and low systemic toxicity for paclitaxel (PTX), a first-line chemotherapeutic agent for vario...

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Autors principals: Zhang, Peng, Huang, Yixian, Liu, Hao, Marquez, Rebecca, Lu, Jianqin, Zhao, Wenchen, Zhang, Xiaolan, Gao, Xiang, Li, Jiang, Venkataramanan, Raman, Xu, Liang, Li, Song
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4102141/
https://ncbi.nlm.nih.gov/pubmed/24856103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.04.108
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