PEG-Derivatized Embelin as a Nanomicellar Carrier For Delivery of Paclitaxel to Breast and Prostate Cancers

Paclitaxel (PTX) is one of the most effective chemotherapeutic agents for a wide spectrum of cancers, but its therapeutic benefit is often limited by severe side effects. We have developed a micelle-based PTX formulation based on a simple conjugate derived from polyethylene glycol 5000 (PEG(5K)) and...

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Autors principals: Lu, Jianqin, Huang, Yixian, Zhao, Wenchen, Marquez, Rebecca T., Meng, Xiaojie, Li, Jiang, Gao, Xiang, Venkataramanan, Raman, Wang, Zhou, Li, Song
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529003/
https://ncbi.nlm.nih.gov/pubmed/23182923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.10.073
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