PEG-Farnesyl Thiosalicylic Acid Telodendrimer Micelles as an Improved Formulation for Targeted Delivery of Paclitaxel

[Image: see text] We have recently designed and developed a dual-functional drug carrier that is based on poly(ethylene glycol) (PEG)-derivatized farnesylthiosalicylate (FTS, a nontoxic Ras antagonist). PEG(5K)-FTS(2) readily form micelles (20–30 nm) and hydrophobic drugs such as paclitaxel (PTX) co...

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Autors principals: Zhang, Xiaolan, Huang, Yixian, Zhao, Wenchen, Chen, Yichao, Zhang, Peng, Li, Jiang, Venkataramanan, Raman, Li, Song
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4123940/
https://ncbi.nlm.nih.gov/pubmed/24987803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500181x
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