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PEG-Farnesyl Thiosalicylic Acid Telodendrimer Micelles as an Improved Formulation for Targeted Delivery of Paclitaxel
[Image: see text] We have recently designed and developed a dual-functional drug carrier that is based on poly(ethylene glycol) (PEG)-derivatized farnesylthiosalicylate (FTS, a nontoxic Ras antagonist). PEG(5K)-FTS(2) readily form micelles (20–30 nm) and hydrophobic drugs such as paclitaxel (PTX) co...
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| Glavni autori: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2014
|
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123940/ https://ncbi.nlm.nih.gov/pubmed/24987803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500181x |
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