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Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

Genetic instability of the mitochondrial genome (mtDNA) plays an important role in human aging and disease. Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability. To address this issue, we developed a model of mtDNA disease in...

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Опубликовано в: :Cell Rep
Главные авторы: Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106782/
https://ncbi.nlm.nih.gov/pubmed/29562168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.099
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