Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

Genetic instability of the mitochondrial genome (mtDNA) plays an important role in human aging and disease. Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability. To address this issue, we developed a model of mtDNA disease in...

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Foilsithe in:Cell Rep
Main Authors: Haroon, Suraiya, Li, Annie, Weinert, Jaye L., Fritsch, Clark, Ericson, Nolan G., Alexander-Floyd, Jasmine, Braeckman, Bart P., Haynes, Cole M., Bielas, Jason H., Gidalevitz, Tali, Vermulst, Marc
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6106782/
https://ncbi.nlm.nih.gov/pubmed/29562168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.099
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