Influence of Inoculum Effect on the Efficacy of Daptomycin Monotherapy and in Combination with β-Lactams against Daptomycin-Susceptible Enterococcus faecium Harboring LiaSR Substitutions

Enterococcus faecium isolates that harbor LiaFSR substitutions but are phenotypically susceptible to daptomycin (DAP) by current breakpoints are problematic, since predisposition to resistance may lead to therapeutic failure. Using a simulated endocardial vegetation (SEV) pharmacokinetic/pharmacodyn...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kebriaei, Razieh, Rice, Seth A., Singh, Kavindra V., Stamper, Kyle C., Dinh, An Q., Rios, Rafael, Diaz, Lorena, Murray, Barbara E., Munita, Jose M., Tran, Truc T., Arias, Cesar A., Rybak, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105850/
https://ncbi.nlm.nih.gov/pubmed/29760141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00315-18
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados