Genomic Pathways Associated with Daptomycin (DAP) Resistance in DAP-Susceptible Enterococcus faecium Harboring Substitutions in LiaFSR

BACKGROUND: DAP is used off-label for treatment of severe enterococcal infections. DAP resistance (R) in E. faecium has been associated with changes in LiaFSR, a three-component regulatory system that controls the cell envelope stress response to antibiotics. In particular, substitutions in LiaS (T1...

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Publicado no:Open Forum Infect Dis
Main Authors: Tran, Truc T, Diaz, Lorena, Rios, Rafael, Dinh, An, Jahanbakhsh, Seyedehameneh, Kebriaei, Razieh, Rybak, Michael J, Arias, Cesar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631937/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.181
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