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Mechanistic Insights Into the Differential Efficacy of Daptomycin Plus β-Lactam Combinations Against Daptomycin-Resistant Enterococcus faecium

BACKGROUND: The combination of daptomycin (DAP) plus ampicillin (AMP), ertapenem (ERT), or ceftaroline has been demonstrated to be efficacious against a DAP-tolerant Enterococcus faecium strain (HOU503). However, the mechanism for the efficacy of these combinations against DAP-resistant (DAP-R) E. f...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Kebriaei, Razieh, Stamper, Kyle C, Singh, Kavindra V, Khan, Ayesha, Rice, Seth A, Dinh, An Q, Tran, Truc T, Murray, Barbara E, Arias, Cesar A, Rybak, Michael J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7529040/
https://ncbi.nlm.nih.gov/pubmed/32514561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa319
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