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HDAC4 degradation by combined TRAIL and valproic acid treatment induces apoptotic cell death of TRAIL-resistant head and neck cancer cells

Although TRAIL can directly induce cell death in some cancer cells, it appears that TRAIL resistance exists in many cancers. This study focuses on anti-cancer drugs for TRAIL-resistant head and neck cancer (HNC) to provide further progress toward effective cancer therapy. Results indicate in TRAIL-r...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Lee, Bok-Soon, Kim, Yeon Soo, Kim, Haeng-Jun, Kim, Dae-Ho, Won, Ho-Ryun, Kim, Yong-Sung, Kim, Chul-Ho
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104079/
https://ncbi.nlm.nih.gov/pubmed/30131570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31039-8
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