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HDAC4 degradation by combined TRAIL and valproic acid treatment induces apoptotic cell death of TRAIL-resistant head and neck cancer cells

Although TRAIL can directly induce cell death in some cancer cells, it appears that TRAIL resistance exists in many cancers. This study focuses on anti-cancer drugs for TRAIL-resistant head and neck cancer (HNC) to provide further progress toward effective cancer therapy. Results indicate in TRAIL-r...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lee, Bok-Soon, Kim, Yeon Soo, Kim, Haeng-Jun, Kim, Dae-Ho, Won, Ho-Ryun, Kim, Yong-Sung, Kim, Chul-Ho
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104079/
https://ncbi.nlm.nih.gov/pubmed/30131570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31039-8
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