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HDAC4 degradation by combined TRAIL and valproic acid treatment induces apoptotic cell death of TRAIL-resistant head and neck cancer cells

Although TRAIL can directly induce cell death in some cancer cells, it appears that TRAIL resistance exists in many cancers. This study focuses on anti-cancer drugs for TRAIL-resistant head and neck cancer (HNC) to provide further progress toward effective cancer therapy. Results indicate in TRAIL-r...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Bok-Soon, Kim, Yeon Soo, Kim, Haeng-Jun, Kim, Dae-Ho, Won, Ho-Ryun, Kim, Yong-Sung, Kim, Chul-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6104079/
https://ncbi.nlm.nih.gov/pubmed/30131570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31039-8
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