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Targeting antigen-specific B cells using antigen-expressing transduced regulatory T cells

Controlling immune responses in autoimmunity and to biotherapeutics is an unmet need. In hemophilia, for example, up to 1/3 of patients receiving therapeutic factor VIII (FVIII) infusions develop neutralizing antibodies termed “inhibitors”. To address this problem in a mouse model of hemophilia A (H...

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Bibliografische gegevens
Gepubliceerd in:J Immunol
Hoofdauteurs: Zhang, Ai-Hong, Yoon, Jeongheon, Kim, Yong Chan, Scott, David W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103823/
https://ncbi.nlm.nih.gov/pubmed/30021767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701800
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