Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses

Expansion of human regulatory T cells (Tregs) for clinical applications offers great promise for the treatment of undesirable immune responses in autoimmunity, transplantation, allergy, and antidrug antibody responses, including inhibitor responses in hemophilia A patients. However, polyclonal Tregs...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kim, Yong Chan, Zhang, Ai-Hong, Su, Yan, Rieder, Sadiye Amcaoglu, Rossi, Robert J., Ettinger, Ruth A., Pratt, Kathleen P., Shevach, Ethan M., Scott, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326771/
https://ncbi.nlm.nih.gov/pubmed/25498909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-566786
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