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Helios controls a limited subset of regulatory T cell functions
A subpopulation (60–70%) of Foxp3(+) T regulatory (Treg) cells in both mouse and man express the transcription factor, Helios, but the role of Helios in Treg function is still unknown. In order to examine the function of Helios in Treg cells, we have generated Treg-specific Helios deficient mice. We...
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| Published in: | J Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685018/ https://ncbi.nlm.nih.gov/pubmed/26582951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501704 |
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