Eos is redundant for T regulatory cell function, but plays an important role in IL-2 and Th17 production by CD4(+) T conventional cells

Eos is a transcription factor that belongs to the Ikaros family of transcription factors. Eos has been reported to be a T regulatory cell (Treg) signature gene, to play a critical role in Treg suppressor functions, and to maintain Treg stability. We have utilized mice with a global deficiency of Eos...

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Rieder, Sadiye Amcaoglu, Metidji, Amina, Glass, Deborah Dacek, Thornton, Angela M., Ikeda, Tohru, Morgan, Bruce A., Shevach, Ethan M.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491037/
https://ncbi.nlm.nih.gov/pubmed/26062998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500627
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items