Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases

During macroautophagy/autophagy, mammalian Atg8-family proteins undergo 2 proteolytic processing events. The first exposes a COOH-terminal glycine used in the conjugation of these proteins to lipids on the phagophore, the precursor to the autophagosome, whereas the second releases the lipid. The ATG...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Kauffman, Karlina J., Yu, Shenliang, Jin, Jiaxin, Mugo, Brian, Nguyen, Nathan, O'Brien, Aidan, Nag, Shanta, Lystad, Alf Håkon, Melia, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper - Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103404/
https://ncbi.nlm.nih.gov/pubmed/29458288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1437341
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