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Toward the function of mammalian ATG12–ATG5-ATG16L1 complex in autophagy and related processes

The machinery that decorates autophagic membranes with lipid-conjugated LC3/GABARAP is not yet fully understood. We recently reported the purification of the full-length ATG12–ATG5-ATG16L1 complex, and in reconstitution experiments with purified ATG7, ATG3, and LC3/GABARAP in vitro, together with re...

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Détails bibliographiques
Publié dans:Autophagy
Auteurs principaux: Lystad, Alf Håkon, Carlsson, Sven R., Simonsen, Anne
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613903/
https://ncbi.nlm.nih.gov/pubmed/31122169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1618100
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