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Distinct functions of ATG16L1 isoforms in membrane binding and LC3B lipidation in autophagy-related processes
Covalent modification of LC3 and GABARAP proteins to phosphatidylethanolamine (PE) in the double-membrane phagophore is a key event in the early phase of macroautophagy, but can also occur on single membrane structures. In both cases this involves transfer of LC3/GABARAP from ATG3 to PE at the targe...
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| Publicado no: | Nat Cell Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7032593/ https://ncbi.nlm.nih.gov/pubmed/30778222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0274-9 |
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