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Dissecting the role of the Atg12–Atg5-Atg16 complex during autophagosome formation

The activity of the conserved Atg12–Atg5-Atg16 complex is essential for autophagosome formation. However, little is known about its mechanism of action during this process. In our study we employed in vitro systems consisting of purified proteins and giant unilamellar vesicles (GUVs) or small liposo...

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Detalhes bibliográficos
Main Authors: Walczak, Marta, Martens, Sascha
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590266/
https://ncbi.nlm.nih.gov/pubmed/23321721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22931
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