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Mechanism and functions of membrane binding by the Atg5–Atg12/Atg16 complex during autophagosome formation
Autophagy is a conserved process for the bulk degradation of cytoplasmic material. Triggering of autophagy results in the formation of double membrane-bound vesicles termed autophagosomes. The conserved Atg5–Atg12/Atg16 complex is essential for autophagosome formation. Here, we show that the yeast A...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
European Molecular Biology Organization
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501226/ https://ncbi.nlm.nih.gov/pubmed/23064152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.278 |
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