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Mechanism and functions of membrane binding by the Atg5–Atg12/Atg16 complex during autophagosome formation

Autophagy is a conserved process for the bulk degradation of cytoplasmic material. Triggering of autophagy results in the formation of double membrane-bound vesicles termed autophagosomes. The conserved Atg5–Atg12/Atg16 complex is essential for autophagosome formation. Here, we show that the yeast A...

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Détails bibliographiques
Auteurs principaux: Romanov, Julia, Walczak, Marta, Ibiricu, Iosune, Schüchner, Stefan, Ogris, Egon, Kraft, Claudine, Martens, Sascha
Format: Artigo
Langue:Inglês
Publié: European Molecular Biology Organization 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501226/
https://ncbi.nlm.nih.gov/pubmed/23064152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.278
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