Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation

Deconjugation of the Atg8/LC3 protein family members from phosphatidylethanolamine (PE) by Atg4 proteases is essential for autophagy progression, but how this event is regulated remains to be understood. Here, we show that yeast Atg4 is recruited onto autophagosomal membranes by direct binding to At...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Abreu, Susana, Kriegenburg, Franziska, Gómez‐Sánchez, Rubén, Mari, Muriel, Sánchez‐Wandelmer, Jana, Skytte Rasmussen, Mads, Soares Guimarães, Rodrigo, Zens, Bettina, Schuschnig, Martina, Hardenberg, Ralph, Peter, Matthias, Johansen, Terje, Kraft, Claudine, Martens, Sascha, Reggiori, Fulvio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412903/
https://ncbi.nlm.nih.gov/pubmed/28330855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643146
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