Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation

Deconjugation of the Atg8/LC3 protein family members from phosphatidylethanolamine (PE) by Atg4 proteases is essential for autophagy progression, but how this event is regulated remains to be understood. Here, we show that yeast Atg4 is recruited onto autophagosomal membranes by direct binding to At...

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Détails bibliographiques
Publié dans:EMBO Rep
Auteurs principaux: Abreu, Susana, Kriegenburg, Franziska, Gómez‐Sánchez, Rubén, Mari, Muriel, Sánchez‐Wandelmer, Jana, Skytte Rasmussen, Mads, Soares Guimarães, Rodrigo, Zens, Bettina, Schuschnig, Martina, Hardenberg, Ralph, Peter, Matthias, Johansen, Terje, Kraft, Claudine, Martens, Sascha, Reggiori, Fulvio
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412903/
https://ncbi.nlm.nih.gov/pubmed/28330855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643146
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