Conserved Atg8 recognition sites mediate Atg4 association with autophagosomal membranes and Atg8 deconjugation

Deconjugation of the Atg8/LC3 protein family members from phosphatidylethanolamine (PE) by Atg4 proteases is essential for autophagy progression, but how this event is regulated remains to be understood. Here, we show that yeast Atg4 is recruited onto autophagosomal membranes by direct binding to At...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Abreu, Susana, Kriegenburg, Franziska, Gómez‐Sánchez, Rubén, Mari, Muriel, Sánchez‐Wandelmer, Jana, Skytte Rasmussen, Mads, Soares Guimarães, Rodrigo, Zens, Bettina, Schuschnig, Martina, Hardenberg, Ralph, Peter, Matthias, Johansen, Terje, Kraft, Claudine, Martens, Sascha, Reggiori, Fulvio
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412903/
https://ncbi.nlm.nih.gov/pubmed/28330855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201643146
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