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Vac8 spatially confines autophagosome formation at the vacuole in S. cerevisiae

Autophagy is initiated by the formation of a phagophore assembly site (PAS), the precursor of autophagosomes. In mammals, autophagosome formation sites form throughout the cytosol in specialized subdomains of the endoplasmic reticulum (ER). In yeast, the PAS is also generated close to the ER, but al...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Hollenstein, David M., Gómez-Sánchez, Rubén, Ciftci, Akif, Kriegenburg, Franziska, Mari, Muriel, Torggler, Raffaela, Licheva, Mariya, Reggiori, Fulvio, Kraft, Claudine
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899017/
https://ncbi.nlm.nih.gov/pubmed/31649143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.235002
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