Reconstitution reveals Ykt6 as the autophagosomal SNARE in autophagosome–vacuole fusion

Autophagy mediates the bulk degradation of cytoplasmic material, particularly during starvation. Upon the induction of autophagy, autophagosomes form a sealed membrane around cargo, fuse with a lytic compartment, and release the cargo for degradation. The mechanism of autophagosome–vacuole fusion is...

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Publicat a:J Cell Biol
Autors principals: Bas, Levent, Papinski, Daniel, Licheva, Mariya, Torggler, Raffaela, Rohringer, Sabrina, Schuschnig, Martina, Kraft, Claudine
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2018
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168255/
https://ncbi.nlm.nih.gov/pubmed/30097514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201804028
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