Φορτώνει......
Maturation and clearance of autophagosomes in neurons depends on a specific cysteine protease isoform, ATG-4.2
In neurons, defects in autophagosome clearance have been associated with neurodegenerative disease. Yet, the mechanisms that coordinate trafficking and clearance of synaptic autophagosomes are poorly understood. Here we use genetic screens and in vivo imaging in single neurons of C. elegans to ident...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Dev Cell |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6482087/ https://ncbi.nlm.nih.gov/pubmed/30880001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.02.013 |
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