Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation

Centromere is a specialized chromatin domain that plays a vital role in chromosome segregation. In most eukaryotes, centromere is surrounded by the epigenetically distinct heterochromatin domain. Heterochromatin has been shown to contribute to centromere function, but the precise role of heterochrom...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Yang, Jinpu, Sun, Siyu, Zhang, Shu, Gonzalez, Marlyn, Dong, Qianhua, Chi, Zhongxuan, Chen, Yu-hang, Li, Fei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6101405/
https://ncbi.nlm.nih.gov/pubmed/30089114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007572
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