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Cell Cycle-Regulated Transcription of CENP-A by the MBF Complex Ensures Optimal Level of CENP-A for Centromere Formation

The centromere plays an essential role in chromosome segregation. In most eukaryotes, centromeres are epigenetically defined by the conserved histone H3 variant CENP-A. Proper centromere assembly is dependent upon the tight regulation of CENP-A level. Cell cycle regulation of CENP-A transcription ap...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Aristizabal-Corrales, David, Yang, Jinpu, Li, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404251/
https://ncbi.nlm.nih.gov/pubmed/30635289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301745
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