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Photoswitchable diacylglycerols enable optical control of protein translocation, PKC activity, and vesicle release
Increased levels of the second messenger lipid diacylglycerol (DAG) induce a variety of downstream signaling events including the translocation of C1 domain-containing proteins toward the plasma membrane. Here, we introduce three light-sensitive DAGs, termed PhoDAGs, which feature a photoswitchable...
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| Udgivet i: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6101201/ https://ncbi.nlm.nih.gov/pubmed/27454932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2141 |
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