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Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance
Cancer cell survival is dependent on oxidative-stress defenses against reactive oxygen species (ROS) that accumulate during tumorigenesis. Here, we show a non-canonical oxidative-stress defense mechanism through TRPA1, a neuronal redox-sensing Ca(2+)-influx channel. In TRPA1-enriched breast and lung...
שמור ב:
| הוצא לאור ב: | Cancer Cell |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6100788/ https://ncbi.nlm.nih.gov/pubmed/29805077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.05.001 |
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