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Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas

DNA editing using CRISPR/Cas has emerged as a potential treatment for diseases caused by pathogenic human DNA viruses. One potential target is HIV-1, which replicates via a chromosomally integrated DNA provirus. While CRISPR/Cas can protect T cells from de novo HIV-1 infection, HIV-1 frequently beco...

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Detaylı Bibliyografya
Yayımlandı:Virology
Asıl Yazarlar: Mefferd, Adam L., Bogerd, Hal P., Irwan, Ishak D., Cullen, Bryan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100742/
https://ncbi.nlm.nih.gov/pubmed/29857168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.05.016
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