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Insights into the mechanisms underlying the inactivation of HIV-1 proviruses by CRISPR/Cas
DNA editing using CRISPR/Cas has emerged as a potential treatment for diseases caused by pathogenic human DNA viruses. One potential target is HIV-1, which replicates via a chromosomally integrated DNA provirus. While CRISPR/Cas can protect T cells from de novo HIV-1 infection, HIV-1 frequently beco...
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| Pubblicato in: | Virology |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6100742/ https://ncbi.nlm.nih.gov/pubmed/29857168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.05.016 |
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