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Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

Even though highly active anti-retroviral therapy is able to keep HIV-1 replication under control, the virus can lie in a dormant state within the host genome, known as a latent reservoir, and poses a threat to re-emerge at any time. However, novel technologies aimed at disrupting HIV-1 provirus may...

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Autors principals: Ebina, Hirotaka, Misawa, Naoko, Kanemura, Yuka, Koyanagi, Yoshio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752613/
https://ncbi.nlm.nih.gov/pubmed/23974631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02510
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