The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA

BACKGROUND: Highly active antiretroviral therapy (HAART) has transformed HIV-1 infection from a deadly disease to a manageable chronic illness, albeit does not provide a cure. The recently developed genome editing system called CRISPR/Cas9 offers a new tool to inactivate the integrated latent HIV-1...

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Publicat a:Retrovirology
Autors principals: Zhu, Weijun, Lei, Rongyue, Le Duff, Yann, Li, Jian, Guo, Fei, Wainberg, Mark A, Liang, Chen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359768/
https://ncbi.nlm.nih.gov/pubmed/25808449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0150-z
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