Doxycycline Attenuates Atrial Remodeling by Interfering with MicroRNA-21 and Downstream Phosphatase and Tensin Homolog (PTEN)/Phosphoinositide 3-Kinase (PI3K) Signaling Pathway

BACKGROUND: Atrial remodeling especially in the form of fibrosis is the most important substrate of atrial fibrillation (AF). The aim of this study was to investigate the effects of doxycycline on chronic intermittent hypoxia (CIH)-induced atrial remodeling and the pathophysiological mechanisms unde...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Med Sci Monit
Päätekijät: Zhang, Kai, Zhao, Linru, Ma, Zuowang, Wang, Weiding, Li, Xiongfeng, Zhang, Yue, Yuan, Meng, Liang, Xue, Li, Guangping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: International Scientific Literature, Inc. 2018
Aiheet:
Animal Study
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100459/
https://ncbi.nlm.nih.gov/pubmed/30098136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.909800
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia