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Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

Approximately one-third of the mammalian proteome is transported from the endoplasmic reticulum-to-Golgi via COPII-coated vesicles. SEC23, a core component of coat protein-complex II (COPII), is encoded by two paralogous genes in vertebrates (Sec23a and Sec23b). In humans, SEC23B deficiency results...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Khoriaty, Rami, Hesketh, Geoffrey G., Bernard, Amélie, Weyand, Angela C., Mellacheruvu, Dattatreya, Zhu, Guojing, Hoenerhoff, Mark J., McGee, Beth, Everett, Lesley, Adams, Elizabeth J., Zhang, Bin, Saunders, Thomas L., Nesvizhskii, Alexey I., Klionsky, Daniel J., Shavit, Jordan A., Gingras, Anne-Claude, Ginsburg, David
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099849/
https://ncbi.nlm.nih.gov/pubmed/30065114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805784115
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