Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

Approximately one-third of the mammalian proteome is transported from the endoplasmic reticulum-to-Golgi via COPII-coated vesicles. SEC23, a core component of coat protein-complex II (COPII), is encoded by two paralogous genes in vertebrates (Sec23a and Sec23b). In humans, SEC23B deficiency results...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Khoriaty, Rami, Hesketh, Geoffrey G., Bernard, Amélie, Weyand, Angela C., Mellacheruvu, Dattatreya, Zhu, Guojing, Hoenerhoff, Mark J., McGee, Beth, Everett, Lesley, Adams, Elizabeth J., Zhang, Bin, Saunders, Thomas L., Nesvizhskii, Alexey I., Klionsky, Daniel J., Shavit, Jordan A., Gingras, Anne-Claude, Ginsburg, David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099849/
https://ncbi.nlm.nih.gov/pubmed/30065114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805784115
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