SEC23B is required for pancreatic acinar cell function in adult mice

Mice with germline absence of SEC23B die perinatally, exhibiting massive pancreatic degeneration. We generated mice with tamoxifen-inducible, pancreatic acinar cell–specific Sec23b deletion. Inactivation of Sec23b exclusively in the pancreatic acinar cells of adult mice results in decreased overall...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Khoriaty, Rami, Vogel, Nancy, Hoenerhoff, Mark J., Sans, M. Dolors, Zhu, Guojing, Everett, Lesley, Nelson, Bradley, Durairaj, Haritha, McKnight, Brooke, Zhang, Bin, Ernst, Stephen A., Ginsburg, David, Williams, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509426/
https://ncbi.nlm.nih.gov/pubmed/28539403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0001
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