Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

Approximately one-third of the mammalian proteome is transported from the endoplasmic reticulum-to-Golgi via COPII-coated vesicles. SEC23, a core component of coat protein-complex II (COPII), is encoded by two paralogous genes in vertebrates (Sec23a and Sec23b). In humans, SEC23B deficiency results...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Khoriaty, Rami, Hesketh, Geoffrey G., Bernard, Amélie, Weyand, Angela C., Mellacheruvu, Dattatreya, Zhu, Guojing, Hoenerhoff, Mark J., McGee, Beth, Everett, Lesley, Adams, Elizabeth J., Zhang, Bin, Saunders, Thomas L., Nesvizhskii, Alexey I., Klionsky, Daniel J., Shavit, Jordan A., Gingras, Anne-Claude, Ginsburg, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2018
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099849/
https://ncbi.nlm.nih.gov/pubmed/30065114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805784115
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