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ER-to-Golgi transport and SEC23-dependent COPII vesicles regulate T cell alloimmunity
T cell–mediated responses are dependent on their secretion of key effector molecules. However, the critical molecular determinants of the secretion of these proteins are largely undefined. Here, we demonstrate that T cell activation increases trafficking via the ER-to-Golgi pathway. To study the fun...
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| Veröffentlicht in: | J Clin Invest |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7810489/ https://ncbi.nlm.nih.gov/pubmed/33463537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136574 |
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