Structural Divergence in O-GlcNAc Glycans Displayed on Epidermal Growth Factor-like Repeats of Mammalian Notch1

Extracellular O-GlcNAc is a novel class of modification catalyzed by epidermal growth factor-like (EGF)-domain specific O-GlcNAc transferase (EOGT). In mammals, EOGT is required for ligand-mediated Notch signaling for vascular development. Previous studies have revealed that O-GlcNAc in mammalian cu...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Ogawa, Mitsutaka, Senoo, Yuya, Ikeda, Kazutaka, Takeuchi, Hideyuki, Okajima, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
Assuntos:
Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099671/
https://ncbi.nlm.nih.gov/pubmed/30018219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23071745
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